产品详情

  • 产品名称：Human CD9 protein (Recombinant) (C-hFC) (STJP001845)

  • 产品型号：STJP001845
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CD9 protein (Recombinant) (C-hFC) (STJP001845)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CD9-C-hFC protein was developed from hek293 cells and has a target region of C-hFC. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD9
Gene ID: 928
Uniprot ID: CD9_HUMAN
Immunogen Region: Ser112-Ile195
Immunogen: Recombinant Human CD9 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser112-Ile195) of human CD9 (Accession #NP_001760.1) fused with and a hFc tag at the C-terminus.
Post Translational Modifications Palmitoylated at a low, basal level in unstimulated platelets. The level of palmitoylation increases when platelets are activated by thrombin (in vitro). The protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids. Palmitoylation by ZDHHC2 regulates CD9 expression, association with other tetraspanin family proteins and function in cell adhesion.
Function Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption. Acts as a receptor for PSG17. Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis.
Protein Name Cd9 Antigen
5h9 Antigen
Cell Growth-Inhibiting Gene 2 Protein
Leukocyte Antigen Mic3
Motility-Related Protein
Mrp-1
Tetraspanin-29
Tspan-29
P24
Cd Antigen Cd9
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-1300645
Reactome: R-HSA-5336415
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Membrane
Secreted
Extracellular Exosome
Present At The Cell Surface Of Oocytes
Accumulates In The Adhesion Area Between The Sperm And Egg Following Interaction Between Izumo1 And Its Receptor Izumo1r/Juno
Alternative Protein Names Cd9 Antigen protein
5h9 Antigen protein
Cell Growth-Inhibiting Gene 2 Protein protein
Leukocyte Antigen Mic3 protein
Motility-Related Protein protein
Mrp-1 protein
Tetraspanin-29 protein
Tspan-29 protein
P24 protein
Cd Antigen Cd9 protein
CD9 protein
MIC3 protein
TSPAN29 protein
GIG2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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