产品名称：Actinin Alpha 2 (ACTN2) Antibody

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles.

Target	Actinin Alpha 2 (ACTN2)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 751-779 amino acids from the C-terminal region of human ACTN2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35609 (UniProt, ExPASy)
UniProt Secondary AC	B1ANE4, B2RCS5, Q86TF4, Q86TI8
UniProt Entry Name	ACTN2_HUMAN
Gene Symbol	ACTN2
KEGG	hsa:88
String	9606.ENSP00000443495
Molecular Weight	Calculated MW: 104 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow ACTN2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Actinin Alpha 2 (ACTN2)