产品详情
简单介绍:
Achaete-Scute Homolog 1 (ASCL1) Antibody
详情介绍:
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Research Articles on Achaete-Scute Homolog 1 (ASCL1)
Target | Achaete-Scute Homolog 1 (ASCL1) |
Clonality | Polyclonal |
Reactivity | Human |
Tested Applications | ELISA, WB |
Host | Rabbit |
Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | KLH-conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human ASCL1. |
Isotype | IgG |
Form | Liquid |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P50553 (UniProt, ExPASy) |
UniProt Secondary AC | A8K3C4, Q9BQ30 |
UniProt Entry Name | ASCL1_HUMAN |
NCBI Accession | NP_004307.2 |
KEGG | hsa:429 |
String | 9606.ENSP00000266744 |
Molecular Weight | Calculated MW: 25.5 kDa |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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