产品名称：ATP Synthase-Coupling Factor 6, Mitochondrial (ATP5PF) Antibody

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the Fo complex, required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. A pseudogene exists on chromosome Yp11.

Target	ATP Synthase-Coupling Factor 6, Mitochondrial (ATP5PF)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 28-56 amino acids from the Central region of human ATP5J.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P18859 (UniProt, ExPASy)
UniProt Secondary AC	J3KQ83
UniProt Entry Name	ATP5J_HUMAN
Gene Symbol	ATP5PF
KEGG	hsa:522
String	9606.ENSP00000389649
Molecular Weight	Calculated MW: 12.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Monkey ATP5PF.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ATP Synthase-Coupling Factor 6, Mitochondrial (ATP5PF)