产品名称：3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1) Antibody

3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta (5) ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosesynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta, 17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta, 17 beta-diol to 5-alpha-dihydrotestosterone.

Target	3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human HSD3B1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P14060 (UniProt, ExPASy)
UniProt Secondary AC	A8K691, Q14545, Q8IV65
UniProt Entry Name	3BHS1_HUMAN
Gene Symbol	HSD3B1
GeneID	3283
OMIM	109715
HGNC	5217
KEGG	hsa:3283
Ensembl	ENSG00000203857
String	9606.ENSP00000358421
Molecular Weight	Calculated MW: 42.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1)